Most sedating antidepressants

A lot of the sedating ones they mention are tricyclics. On the other hand, if you're healthy and not at risk of od'ing then maybe they'd be right for you.

Those are older ad's, that again, should probably be prescribed by a psychiatrist, rather than a GP - since most GPs won't be that familiar with them. Serzone isn't prescribed much nowadays either - I think because it's not that effective? Mouse's suggestion, Remeron, is supposed to be sedating.

A standard one used is Depakote, for wich the dosage is by far easier to adjust that Lithium. It has a very sedating effect, and also gives a crazy appitite, but for the first yr I was on it, I mananged to maintain my weight, but alas I sucumb to the effets of Remeron eventually and am now heavier than I would like to be, but the anxiety is much easier because of the meds so I am learning to love myself with the extra weight because these AD's are quite wonderful for me really :-) Hello, Prozac is well known to provoke mania or hypomanic state in people.

Pros: An SNRI that’s generally well tolerated if started in low doses.

Pros: A very effective SSRI that can be easier to start and stay on than others.

Side effects: Nausea, insomnia, headaches, sexual dysfunction, jitteriness; possibly drowsiness, dry mouth, constipation.

It’s the worst one for weight gain, and among the worst for withdrawal symptoms (unless properly managed).

Whom it may be suitable for: Those whose depression causes fatigue; also ideal for anxiety symptoms and anxiety disorders; not ideal where weight gain is a health concern.

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